Marcella is a stand up comedian, writer and actor whose comedy knows no bounds; she eagerly discusses any and every topic that tickles her. From dating short guys – because she has no other options at 6’2’’ – to being mistaken for a man, her Latinx identity, her take on race & gender, and wild stories & situations she’s gotten herself in and out of. Marcella’s debut half hour comedy special Bitch, Grow Up. was released in 2023 on HBO MAX. It’s a half hour that fully represents the comedians abilities to handle all forms of comedy – from one liners to stories to crowd work – the seventeen years she’s put in absolutely shines through. Of the special, Latin Media writes that Marcella “manages to ruffle feathers while delivering a routine that feels absolutely joyous.” Decider.com writes, “she has earned this moment.”

In 2024, Marcella kicked off the year as a regular guest of After Midnight on CBS and made a great first impression according to Vulture. She also debuted her monthly show, Comedy Is Dead! in Chicago the second Thursdays of the month at Lincoln Lodge. The show is a result of her podcast of the same name, which tackles her experience with the industry and why she feels stand up is currently in a strange place. She hopes it inspires more comedians to put more care in their craft and helps audiences appreciate stand up. She is also currently working on her first solo show. She is most proud of her (now retired) monthly show, Women Crush Wednesdays, which always had a fresh and diverse line up, including national headliners as well as the brightest up and comers; Marcella mercilessly hosted the best curated show in all of Los Angeles and she’s happy to have provided numerous opportunities to many comedians because of it. Her debut album, The Woke Bully – which debuted at #3 on the Billboard Comedy Charts and was named One Of The Best Comedy Albums of 2019 by NPR program Bullseye – is a combination of Marcella’s unique perspective & honesty and captures what it’s like to experience her live. Her follow up album, Mercury in Reggaeton, is a collection of rejected material from her debut special and is a perfect depiction of her ability to go with the flow of a live show. Marcella also recorded, Motivational Monday Meditations with Marcella Marguello, a comedic meditation album that is loved by anyone who listens.

In 2023, she can be seen on Fuse TV’s second season of We Need To Talk About America, where first generation comedians dissect American-centric topics and viral videos. Marcella was also the host of The Cache on Tubi in 2021, a hilarious clip show that infuses Marcella’s unique perspective on viral videos. In 2020, COVID-19 halted the entertainment industry but Marcella managed to guest star in Sarah Cooper’s Netflix Special Everything’s Fine, was seen as a panelist on David Spade’s Lights Out on Comedy Central, killed her over-the-top dance numbers on The Funny Dance Show on E! and had a covid compliant interview on FuseTV’s Like, Share, Dímelo. Her stand up can be seen on the second season of 2 Dope Queens on HBO as well as Night Train with Wyatt Cenac on STARZ; previously she has made a guest appearance on Comedy Central’s Corporate and on episodes of FuseTV’s Trivial Takedown. Recently MSN.com listed Marcella as number 10 in their list of “Top female comedians working in film and television today.” In the Fall of 2017, Vulture.com presented their list of “Comedians You Should and Will Know” and Marcella was the top industry pick which gaind her a feature in the November issue of New York Magazine. Marcella was deemed an “LA Comedian to Watch in 2017” by Time Out Magazine while maintaining her reign as a fan favorite and six-time winner on Comedy Central’s @midnight. She wrote for the renewed Netflix series “Bill Nye Saves The World” and was a writer on the first season of the James Corden-produced show, Drop The Mic on TBS.  Additionally, Marcella won her appearance on TruTv’s Comedy Knock Out, was featured on Viceland’s Flophouse, and in 2015 on NBC’s Last Call with Carson Daly; her stand up has been highlighted on rapper Tyler, The Creator’s mobile app and on Fox’s The Real.

Her controversial takes on Twitter (@marcellacomedy) have featured the comedian on CNN, Glamor Magazine, Fox, TIME.com, HuffingtonPost.com and various other entertainment websites. She is a regular opener for Hasan Minhaj, Ralph Barbosa, Nicole Byer, Melissa Villaseñor and Nico Santos. She has previously opened for Felipe Esparza, Michelle Buteau, Hannibal Buress, David Alan Grier, Cheech Marin, Norm MacDonald, J.B. Smoove, Aida Rodriguez, Phoebe Robinson, Al Madrigal, Ron Funches, Godfrey, Pablo Francisco, Joey Coco Diaz, Melanie Comarcho and many,many more. She has also been privileged to share the stage with Bill Burr, Mark Curry, Jerry Seinfeld, Paul Mooney and Robin Williams.

She has worked at The Improv Comedy Clubs all over the country and is a regular at The Punch Line Comedy Clubs in Northern California. She has performed at The New York Comedy Festival, Bridgetown Comedy Festival, Chris Hardwick’s ID10T Festival, Riot LA Comedy Festival, Lucille Ball Comedy Fest, overseas for American troops and comedian Sean Keane referred to her as the “finest export from Modesto since George Lucas.”